The effect of diabetes and undernutrition trends on reaching 2035 global tuberculosis targets

The third of a three-part Lancet series on diabetes and TB:

To achieve the post-2015 global tuberculosis target of 90% reduction in tuberculosis incidence by 2035, the present rate of decline must accelerate. Among factors that hinder tuberculosis control, malnutrition and diabetes are key challenges. We review available data to describe the complex relationship between tuberculosis, diabetes, and nutritional status. Additionally, we review past trends, present burden, and available future global projections for diabetes, overweight and obesity, as well as undernutrition and food insecurity. Using a mathematical model, we estimate the potential eff ect of these factors on tuberculosis burden up to 2035. Great potential exists for reduction of worldwide tuberculosis burden by combination of improved prevention and care of diabetes with reduction of undernutrition. To achieve this combination will require joint eff orts and strong cross-programme links, enabling synergistic eff ects of public health policies that promote good nutrition and optimum clinical care for tuberculosis and diabetes.

Document Date: 16 September, 2014
Author: Anna Odone, Rein M G J Houben, Richard G White, Knut Lönnroth